COMPARATIVE ANALYSIS OF THE COURSE OF TUBERCULOSIS IN PATIENTS, WHO HAVE AND HAVE NOT HAD COVID-19

Currently, TB hospitals receive a large number of patients with newly diagnosed pulmonary tuberculosis, as well as patients with relapse who were already on the dispensary register after suffering COVID-19. Based on this, it is of great interest to study the features of the course of tuberculosis after a new coronavirus infection. In this work, a study was conducted in which 30 patients were included, divided into 2 groups. 15 patients had a new coronavirus infection (the main group), and the other half did not have COVID-19 (comparative group). All patients were treated at the State Budgetary Institution Republic of Sakha Yakutia «Scientific and Practical Center of Phthisiology named after E.N. Andreev» in Yakutsk from 2020 to 2022. Upon admission to the infectious diseases department, all patients underwent: determination of SARSCoV- 2 RNA by PCR, ELISA for the presence of antibodies (IgM and IgG), general clinical tests, sputum examination for bacterial release of mycobacterium tuberculosis, instrumental studies. According to the results of the study, the following was revealed: male, middle-aged persons prevailed; in most patients who underwent COVID-19, the clinical picture was not bright, without complaints; in most patients, a new coronavirus infection occurred in mild form; complications of pulmonary tuberculosis occurred only in the main group; there is a lethal outcome in the main group due to multiple organ insufficiency.